‘Accidental’ supplementation is no joke when you are sponsored by a supplement company… Iljo Keisse has faced the Belgian Cycling Federation (RLVB) in relation to the hydrochlorothiazide (HCT) and cathine found in his urine on the last day of the Gent Six Day late last year. The federation is seeking a two-year sanction for Keisse, and the debate has now begun as to whether the presence of the HCT and cathine was intentional.
HCTZ is a diuretic, used to block salt and fluid re-absorption in the kidneys, increasing the release of urine. For an athlete that may assist by more quickly clearing wastes and byproducts from the system, masking use of ‘something else’.
Cathine is an appetite suppressant and may have a stimulant effect. For an athlete this may assist in weight control and/or give the competitor a physical (or perhaps psychological) boost.
Filed under
cathine,
HCTZ,
Keisse by
Rob.
‘Accidental’ supplementation is no joke when you are sponsored by a supplement company… Iljo Keisse has faced the Belgian Cycling Federation (RLVB) in relation to the hydrochlorothiazide (HCT) and cathine found in his urine on the last day of the Gent Six Day late last year. The federation is seeking a two-year sanction for Keisse, and the debate has now begun as to whether the presence of the HCT and cathine was intentional.
HCTZ is a diuretic, used to block salt and fluid re-absorption in the kidneys, increasing the release of urine. For an athlete that may assist by more quickly clearing wastes and byproducts from the system, masking use of ‘something else’.
Cathine is an appetite suppressant and may have a stimulant effect. For an athlete this may assist in weight control and/or give the competitor a physical (or perhaps psychological) boost.
Filed under
cathine,
HCTZ,
Keisse by
Rob.
Another one bites the dust… Team Topsport-Vlaanderen fired Iljo Keisse on Monday, following the official notification that the Belgian rider’s B sample had come back positive. The Six-Day rider tested positive for two substances, cathine and hydrochlorothiazide (HCTZ), at the Gent Six Day Race the end of November.
Cathine: Closely related to ephedrine, cathinone and other amphetamines, it may contribute to the stimulant effect of Catha edulis, although another constituent, cathinone appears to show stronger activity. Cathine is one of the optical isomers of phenylpropanolamine, an appetite suppressant and decongestant which is possibly associated with an increased risk of hemorrhagic stroke. An appetite suppressant, so probably useful in keeping your weight down. Also a stimulant, so it may make you more aggressive and motivated.
HCTZ:Hydrochlorothiazide belongs to the thiazide class of diuretics, acting on the kidneys to reduce sodium (Na) reabsorption in the distal convoluted tubule. This increases the osmolarity in the lumen, causing less water to be reabsorbed by the collecting ducts. This leads to increased urinary output. A blood thickener and a diuretic; hard to see much benefit for a cyclist… unless of course it helps get other drugs out of the system before a blood test.
Filed under
cathine,
HCTZ,
Keisse by
Rob.
Another one bites the dust… Team Topsport-Vlaanderen fired Iljo Keisse on Monday, following the official notification that the Belgian rider’s B sample had come back positive. The Six-Day rider tested positive for two substances, cathine and hydrochlorothiazide (HCTZ), at the Gent Six Day Race the end of November.
Cathine: Closely related to ephedrine, cathinone and other amphetamines, it may contribute to the stimulant effect of Catha edulis, although another constituent, cathinone appears to show stronger activity. Cathine is one of the optical isomers of phenylpropanolamine, an appetite suppressant and decongestant which is possibly associated with an increased risk of hemorrhagic stroke. An appetite suppressant, so probably useful in keeping your weight down. Also a stimulant, so it may make you more aggressive and motivated.
HCTZ:Hydrochlorothiazide belongs to the thiazide class of diuretics, acting on the kidneys to reduce sodium (Na) reabsorption in the distal convoluted tubule. This increases the osmolarity in the lumen, causing less water to be reabsorbed by the collecting ducts. This leads to increased urinary output. A blood thickener and a diuretic; hard to see much benefit for a cyclist… unless of course it helps get other drugs out of the system before a blood test.
Filed under
cathine,
HCTZ,
Keisse by
Rob.
